Phytochemical screening of ethanolic leaf extract of eichhornia crassipes for antimalarial activity

Abstract

Malaria is a parasitic infection caused by a parasite that spends part of its life in people and the rest in mosquitos. Malaria continues to be one of the world's worst killers, threatening the lives of more than a third of the world's population. Treatments with organophosphates and insect growth regulators are the main control tools against Anopheles larvae, but they have negative effects on human health and the environment. Green control tools are a priority in this circumstance and are required for mosquito control. In this present study, Positive and negative controls were orally provided in mice for 24 hours before several tests were conducted out in the current investigation to evaluate the Treatment of Ethanolic extracts of Eichhornia crassipes. Mice were used in the Acute Toxicity Tests, the Early Malaria Infection Test, and the Established Infection Method Test. Asthenia, piloerection, ataxia, anorexia, urination, diarrhoea, lethargy, and coma were among the behavioural signs of toxicity observed in the mice. As a result, Eichhornia crassipes extract appears to have significant malarial activity. As a result, Eichhornia crassipes could be used as a natural antiplasmodial agent for the fight against Malaria.