Elaborated studies on Schiff base homo-binuclear Cu(II) and Co(II) complexes, spectral, thermal, P-XRD and biocidal studies

Abstract

A homo-binuclear Cu(II) and Co(II) complexes were synthesized using a Schiff base ligand derived by condensation of 2,6-diaminopyridine and glyoxal. The reasonable geometry of the Schiff base and its binucleating metal complexes were examined by means of elemental and thermal analyses, molar conductance, ¹HNMR, UV–Vis, IR, ESR, P-XRD and mass spectra. The ligand behaved as a polydentate, coordinating through the nitrogen atom of the azomethine group, a nearest nitrogen atom of the pyridine group and the oxygen atom of a glyoxal group. From the spectral studies, a six coordinate environment around the metal dimers was confirmed. The binuclear nature of the metal complexes was assessed from their magnetic susceptibility values. Both of the Schiff base and its metal complexes were also tested for their in vitro antimicrobial activities against some bacterial and fungal strains. Schiff base and the metal complexes were also investigated for its cytotoxic effect against human breast cancer (MCF7) cell lines.